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what is the pathophysiology of dengue fever inside the body? how does it reacts

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what is the pathophysiology of dengue fever inside the body? how does it reacts
Best answer: Dengue virus affects the Reticuloendothelial system (RE System) and therefore we see petichae, platelet consumption coagulopathy and bleeding disorders. This can be severe enough so as to warrant infusion of fresh platelets or in the ab
Best answer:
Dengue virus affects the Reticuloendothelial system (RE System) and therefore we see petichae, platelet consumption coagulopathy and bleeding disorders. This can be severe enough so as to warrant infusion of fresh platelets or in the absence of the blood fractions, whole blood may have to be used in order to raise and maintain the levels of platelets in the body. The gross effect is directly seen over the spleen and the smaller arterioles and venioles. The other manifestation of the disease such as fever, aches, prostration, are because of the activation of cytokinins and the release of the mediators of the inflammation.
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