is Hepatitis B,curable? can u still live a normal life? for how long though?
|
|
From:Internet By:Internet |
|
is Hepatitis B,curable? can u still live a normal life? for how long though?
what is the cost of the medication to control it?pls give estimate in doller terms,if possible. Best answer: The natural history of chronic HBV infection can vary dramatically between individuals. Some will develop a condition commonly referred to as
what is the cost of the medication to control it?pls give estimate in doller terms,if possible.
Best answer:
The natural history of chronic HBV infection can vary dramatically between individuals. Some will develop a condition commonly referred to as a chronic carrier state. These patients, who are still potentially infectious, have no symptoms and no abnormalities on laboratory testing. Nonetheless, some of these patients will have evidence of hepatitis on liver biopsy.
Some individuals with chronic hepatitis B will have clinically insignificant or minimal liver disease and never develop complications. Others will have clinically apparent chronic hepatitis. Some will go on to develop cirrhosis. Individuals with chronic hepatitis B, especially those with cirrhosis but even so-called chronic carriers, are at an increased risk of developing hepatocellular carcinoma (primary liver cancer). Although this type of cancer is relatively rare in the United States, it is the leading cause of cancer death in the world, primarily because HBV infection is endemic in the East.
Chronic infection with HBV can be either "replicative" or "non-replicative." In non-replicative infection, the rate of viral replication in the liver is low and serum HBV DNA concentration is generally low and hepatitis Be antigen (HBeAg) is not detected. HBeAg is an alternatively processed protein of the pre-core gene that is only synthesized under conditions of high viral replication. In "replicative" infection, the patient usually has a relatively high serum concentration of viral DNA and detectable HBeAg. Patients with chronic hepatitis B and "replicative" infection defined by the presence of detectable HBeAg have a generally worse prognosis and a greater chance of developing cirrhosis and/or hepatocellular carcinoma than those without HBeAg. In rare strains of HBV with mutations in the pre-core gene, "replicative" infection can occur in the absence of detectable serum HBeAg.The diagnosis of HBV infection is generally made on the basis of serology. Virtually all individuals infected with HBV, either acutely or chronically, will have detectable serum hepatitis B surface antigen (HBsAg). In acute infection, HBsAg is detectable several weeks after infection and its appearance coincides with the onset of clinical symptoms. HBeAg is also detectable in acute infection which is characterized by a high rate of viral replication. At around the same time, IgM antibodies against core antigen are detectable in serum. Subsequently, IgG antibodies against core are produced. As acute infection resolves, IgG antibodies against core antigen persist and IgM antibodies and HBsAg become undetectable. Subjects who develop an immune response against HBV develop antibodies against HBsAg. Such antibodies are also produced by vaccination. Most people who have had acute infection that resolves continue to have IgG antibodies against core antigen for life. Some remain immune with antibodies against HBsAg but some lose these antibodies and may be susceptible to future infection.
In individuals suspected of having chronic hepatitis B, the appropriate screening test is for serum HBsAg. Individuals who may have chronic hepatitis B who should be considered for testing include:
Those with symptoms of chronic liver disease
Those with abnormal laboratory tests suggesting liver disease
Those with risk factors such as past intravenous drug use or unprotected promiscuous sex
Children of HBV infected parents or household contacts
Health care workers
Patients on hemodialysis
Individuals in the above groups who do not have chronic hepatitis B should be offered vaccination as most remain at increased risk of acquiring infection.
|
| PageUp:NOLVADEX do you anything about it please? PageDown:Do I have cervical cancer? |
|
[ Collection]
[ Recommend]
[ Comments(0)]
[Top] [Print]
[Closed] |
|
|
| |
|
|
 |
|
WebsiteAD |
|
|
|
|
|
